Dietary restriction (DR or calorie restriction) is an evolutionarily conserved intervention that extends healthy lifespan. I am interested in the nutrients and molecular mechanisms required to elicit this effect – in particular the role of protein. Knowledge of these interactions will aid our understanding of the role of nutrient balance in adult health, appetite and longevity.
|2020 – present||Senior Lecturer, Monash University|
|2016 – 2020||ARC Future Fellow, Monash University|
|2010 – 2016||Royal Society University Senior Research Fellow, UCL|
|2002 – 2010||Wellcome Trust Postdoctoral Research Fellow, UCL|
|2001 – 2002||Tenure-track researcher, Technical University of Delft, The Netherlands|
|1997 – 2001||PhD in Biochemistry and Molecular Genetics, UNSW, Australia|
|1996||Honours [First Class] Molecular Genetics, UNSW, Australia|
|1993 – 1995||Bachelor of Science, University of Adelaide, Australia|
|2020 – 2022||National Health and Medical Research Centre||Ideas Grant|
|2016 – 2020||Australian Research Council||Future Fellowship|
|2012||Wellcome Trust||Wellcome Trust People Awards|
|2012||UCL Crucible Centre||Art/science collaboration|
|2012||AGE UK||Art/science collaboration|
|2012 – 2015||Royal Society||URF research grant|
|2011 – 2016||Royal Society||University Research Fellowship|
|2011 – 2014||BBSRC||New Investigator Award|
|2011 – 2015||UCL Crucible Centre (Medical Research Council)||4y PhD studentship|
|2016 – current||Research Assistant – Monash University, Australia|
|2015 – 2016||Research and Development Scientist – MiniFab, Australia|
|2012 – 2014||Project Manager – The University of Queensland, Australia|
|2010 – 2012||Laboratory Manager – StemLife, Australia|
|2007 – 2009||Research Assistant – Australian Institute for Bioengineering and Nanotechnology, Australia|
|2004 – 2006||Research Assistant – Queensland Brain Institute, Australia|
|2002 – 2004||Research Technician – University of Ulm, Germany|
|2001||Honours, The University of Newcastle, Australia|
|1998 – 2000||Bachelor of Science (Biotechnology), The University of Newcastle, Australia|
I obtained a Bachelor of Science degree at the Universidade de São Paulo (Brazil – 2011) studying the effects of oxidative stress on lymphocytes. In 2015, at the same University, I completed my Master’s investigating the relationship between nutrition and aging in honeybees. In 2020, I obtained my PhD from the University of Melbourne investigating how contaminating insecticides doses reprogram insect metabolism, causing oxidative stress leading to neurodegeneration. I spent 6 months of my PhD at the Baylor College of Medicine (Houston, TX). Currently, as a postdoc, I am modelling and seeking dietary interventions for inborn errors of metabolism. I have a passion for biology and when I am not in the lab I love spending time with my family, being in touch with nature or playing violin.
I completed my undergrad studies in Universidad Autónoma de Madrid (including one year abroad in the University of York). Afterwards I did my MRes in The University of Liverpool. I did my undergrad research project on vascular mouse models of accelerated ageing. Keeping in the line of ageing research my MRes project was based on the study of Protein and Gene Co-expression networks of Cellular Senescence. For my PhD, I would like to deepen into network analysis and other system biology analysis of ageing and it’s relationship with diet and fitness in Drosophila melanogaster. I am brand new in Melbourne so in my free time I would love to travel around and go hiking to explore the nature in Australia.
I completed my undergraduate degree in Biotechnology at SASTRA University, India. I was presented with an opportunity to do my final year project in the University of Oxford, where I tried to understand how various autophagy inducers can treat monogenic disease associated with intestinal inflammation. I then pursued a MRes in Clinical Medicine in Holm Uhlig’s lab at the University of Oxford, where I investigated the mechanisms by which defective G6PT metabolism in macrophages potentiate the intestinal inflammation in patients with Crohn’s disease. For my PhD, I would be using various genetic tools to understand how nutrition affects infection and immunity in D.melanogaster. Outside of academic life, I would like to get involved with activism. I also enjoy quiet reading and going to cheesy musicals.
I started my undergraduate degree at the University of Queensland, studying Journalism and International Relations. During my degree I became involved in scientific communication and as a result, transferred to a Bachelor of Science at Monash University. I completed both my undergraduate and honours year at Monash University, majoring in Ecology and Conservation Biology. Throughout my honours year I studied the role of nutrition in mediating larval trait responses to temperature in different populations of D. melanogaster. Now, during my PhD I intend to study the effects of sterols and other less examined nutrients on lifespan and reproductive trade-offs in D. melanogaster, and the mechanisms behind such trade-offs. In my spare time I enjoy photography, long walks in the forest and reading.
I completed my undergraduate degree at Monash University majoring in both chemistry and genetics. For my honours year, Matt supervised my project looking at the effects of dietary pretreatment on subsequent stress tolerance. My PhD project is continuing on from my honours project with a broader scope to understand how diets can alter responses to stress. I spend my free time outside when the weather is nice, otherwise I am reading or playing video games.
I recently completed my bachelor degree in Monash University, majoring in Biomedical Science. I have a particular interest in how dietary manipulation can improve the phenotype of diseased individuals. I’m currently working on my honours project which aims to develop a diet to treat an inborn error of amino acid metabolism. Outside the lab I enjoy traveling with my families and friends.
I’m currently completing the honours year of my Bachelor of Science at Monash University, where I have majored in genetics. I’ve long been interested in understanding why and how organisms age, and thus would like to improve knowledge of the underlying mechanisms of ageing and their regulators. In the lab I’m investigating one such regulator of ageing, being nutrition, and more specifically how manipulating individual dietary amino acids affects life span and lifelong health in Drosophila melanogaster. Outside the lab I enjoy surfing, reading and tending to my many house plants.
I am currently undertaking my honours year in a Bachelor of Science Advanced- Research at Monash University, having majored in Genetics and Immunology. I am particularly interested in the genetic influences on disease and how gene expression can be modulated. My honours project involves examining the effects of dietary manipulation on a Drosophila model of the metabolic disease, Phenylketonuria. Outside of the lab I enjoy fossicking and playing the piano.
Carolyn Ma – Masters Student
Study scientist at Applied Insect Science, UK
Arani Azim – Masters Student
Title of Research: Determining The Role Of Drosophila Salt Inducible Kinase 3 In Animal Growth In Relation To Dietary Nutrients
Lisa Rapley – Honours student
Title of Research: How diet, specifically protein, impacts immune function
Helen Rushby – Honours student
Title of Research: Flies, smell and appetite
Rob di Paolo – Honours student
Title of Research: Drosophila microbiota and amino acid supply
Andrea Chan – Honours student
Title of Research: Amino acid deficits and toxicity hardening
Sasha Pollock – Honours student
Title of Research: The role of essential amino acids in lifespan
Iris Bouwmeester – Dutch visiting student
Title of Research: Flies, nutrition and cold stress